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The Tottenham defender scored on two occasions as Tottenham extended their unbeaten run on the road in the top division and handed the Toffees their first defeat at their new home.

Everton were unbeaten in their five previous fixtures at their recently opened stadium at the dockside location, having left Goodison Park behind after 133 years at the conclusion of last season.

But Tottenham's leader Van de Ven pounced on two occasions from corners in the first half to put their impressive record at jeopardy, and they were unable to mount a comeback before the midfielder - assisted by ex-Everton forward Richarlison - nodded in a third to put the game to bed.

The Everton defender thought he had equalized the scores a short while after the defender's first goal, glancing a bullet header past the Spurs keeper from an set-piece.

Beto, in the meantime, failed to convert a handful of chances, while the Italian goalkeeper made a series of excellent stops to ensure the London club went five away games unbeaten in the Premier League.

But the video assistant referee intervened, advising Craig Pawson to check the goal on the screen and the referee decided that Jack Grealish and the attacker were in offside positions and had interfered with the Spurs keeper.

This victory elevates Thomas Frank's side into third place in the division, five points off local foes and leaders Arsenal.

The Merseyside club remain in 14th position and sit half a dozen points ahead of the drop zone.

Tottenham analysis: Van de Ven fulfils duties at both ends of pitch

After a drab weekday performance in the Champions League against the French side, where they managed a mere two shots on goal, Frank chose Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.

The summer signing was failed to influence the game before being replaced for Richarlison after an hour on the field, but it turns out he wasn't needed in the end.

Defender the Dutchman converted into an attacking force to be reckoned with.

Tottenham's opening strike came from a cleverly executed corner routine, with the midfielder heading the ball back across the six-yard box for an free the defender to head home.

And Ven de Ven - filling in as skipper in the Argentine's unavailability - added his next goal in first-half stoppage time as he outjumped the England keeper to head home.

The Dutchman was just as impressive in defensive duties, partnering well with Kevin Danso as the duo handled excellently with the 34 crosses sent their way by the opposition.

Toffees breakdown: Everton missing striker's instinct

Everton's recent stadium had been a fortress, but it appears the novelty may have worn off slightly and fans flocked to the gates after the midfielder's third for Spurs.

The break in Everton's winning streak at home won't be a massive worry for David Moyes, but their attacking woes are.

Beto and Thierno Barry - the Everton's pair of recognised centre-forwards - had scored only a single goal between them before the weekend's match.

And they were unable to add to that poor tally on a wet and gloomy night on Merseyside.

The striker's form was summed up when he opted to bicycle-kick a golden opportunity from close range, despite having room and time to readjust for a simpler shot that would have challenged the keeper.

Barry, as well, was unable to influence the game after coming on for Beto in the 65th minute.

It was not for a shortage of chance. Most of the home side's offensive moves came through the winger and the forward, who relentlessly whipped dangerous crosses into the Spurs penalty area.

What next for these two sides?

The Toffees: Moyes' men travel to Sunderland in the top flight on early November at 20:00 GMT.

Tottenham: The London club travel to St James' Park on late October for their fourth-round League Cup match against the Magpies.